BDBM50243896 (1S,5R)-1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane::(1S,5R)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane::CHEMBL488638

SMILES Clc1ccc(cc1Cl)[C@]12C[C@H]1CNC2

InChI Key InChIKey=BSMNRYCSBFHEMQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50243896   

TargetTransporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243896((1S,5R)-1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0...)
Affinity DataIC50: 430nMAssay Description:Inhibition of norepinephrine uptake at NET in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243896((1S,5R)-1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0...)
Affinity DataIC50: 66nMAssay Description:Inhibition of serotonin uptake at SERT in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243896((1S,5R)-1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0...)
Affinity DataIC50: 330nMAssay Description:Inhibition of dopamine uptake at cloned DAT in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243896((1S,5R)-1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0...)
Affinity DataIC50: 103nMAssay Description:Inhibition of norepinephrine uptake at human cloned NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243896((1S,5R)-1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0...)
Affinity DataIC50: 133nMAssay Description:Inhibition of serotonin uptake at human cloned SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243896((1S,5R)-1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0...)
Affinity DataIC50: 129nMAssay Description:Inhibition of dopamine uptake at human cloned DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed