BDBM50243885 4-[(2,6-Difluorobenzyl)amino]-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide::CHEMBL519410

SMILES NC(=O)c1cnc(Nc2ccc(cc2)N2CCOCC2)nc1NCc1c(F)cccc1F

InChI Key InChIKey=KJXQRRSXUAURNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50243885   

TargetSignal transducer and activator of transcription 6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243885(4-[(2,6-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of STAT6 activation in FW4 reporter cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed