BDBM50243745 CHEMBL4076989
SMILES CC(C)CN(CCc1ccc(Cl)cc1)C1CCN(CC1)c1nc(N)n[nH]1
InChI Key InChIKey=BADSWYIEDNZIEB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50243745
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Oncoarendi Therapeutics
Curated by ChEMBL
Oncoarendi Therapeutics
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of tracer red binding to human ERG expressed in HEK293 cell membranes measured after 2 to 6 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of full-length C-terminal his-tagged mouse AMCase expressed in expressed in CHO-K1 cells assessed as reduction in chitinolytic activity us...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of full-length C-terminal his-tagged human AMCase expressed in CHO-K1 cells assessed as reduction in chitinolytic activity using 4-methylu...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...More data for this Ligand-Target Pair
Affinity DataIC50: 232nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged chitotriosidase expressed in CHO-K1 cells using 4-methylumbelliferyl-beta-D-N,N',N"...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Oncoarendi Therapeutics
Curated by ChEMBL
Oncoarendi Therapeutics
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of [3H]-astemizole binding to human ERG after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...More data for this Ligand-Target Pair
Affinity DataIC50: 2.96E+3nMAssay Description:Inhibition of mouse recombinant full length C-terminal His-tagged chitotriosidase expressed in CHO-K1 cells using 4-methylumbelliferyl-beta-D-N,N',N"...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of full length recombinant C-terminal His-tagged human acidic mammalian chitinase expressed in CHOK1 cells assessed as reduction in chitin...More data for this Ligand-Target Pair
Affinity DataIC50: 229nMAssay Description:Inhibition of full length recombinant C-terminal His-taged human CHIT1 expressed in CHOK1 cells assessed as reduction in chitinolytic activity using ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Oncoarendi Therapeutics
Curated by ChEMBL
Oncoarendi Therapeutics
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Displacement of Tracer Red from human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 232nMAssay Description:Inhibition of full-length C-terminal his-tagged human recombinant CHIT1 catalytic domain (1 to 386 residues) expressed in HEK293F cells assessed as r...More data for this Ligand-Target Pair
Affinity DataIC50: 2.96E+3nMAssay Description:Inhibition of recombinant full-length C-terminal his-tagged mouse CHIT1 expressed in CHO-K1 cells assessed as reduction in chitinolytic activity usin...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...More data for this Ligand-Target Pair
Affinity DataKi: 312nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged chitotriosidase expressed in CHO-K1 cells using 4-methylumbelliferyl-beta-D-N,N',N"...More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Inhibition of mouse recombinant full length C-terminal His-tagged chitotriosidase expressed in CHO-K1 cells using 4-methylumbelliferyl-beta-D-N,N',N"...More data for this Ligand-Target Pair