BDBM50243472 1-(5-(4-(2-(diethylamino)ethoxy)phenyl)-3-(pyridin-3-ylcarbamoyl)thiophen-2-yl)urea::CHEMBL460888

SMILES CCN(CC)CCOc1ccc(cc1)-c1cc(C(=O)Nc2cccnc2)c(NC(N)=O)s1

InChI Key InChIKey=BKJYSELXLJGLNW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243472   

TargetSerine/threonine-protein kinase Chk1(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243472(1-(5-(4-(2-(diethylamino)ethoxy)phenyl)-3-(pyridin...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2-associated protein 1(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243472(1-(5-(4-(2-(diethylamino)ethoxy)phenyl)-3-(pyridin...)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of Cdk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed