BDBM50243208 CHEMBL486043::trans-3-(o-tolyloxy)-2,3-dihydro-1H-inden-1-amine

SMILES Cc1ccccc1O[C@H]1C[C@H](N)c2ccccc12

InChI Key InChIKey=VQMGCAXPAOTPQE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243208   

TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243208(trans-3-(o-tolyloxy)-2,3-dihydro-1H-inden-1-amine ...)
Affinity DataIC50: 600nMAssay Description:Inhibition of dopamine uptake at human DAT in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243208(trans-3-(o-tolyloxy)-2,3-dihydro-1H-inden-1-amine ...)
Affinity DataIC50: 840nMAssay Description:Inhibition of norepinephrine uptake at human NET in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243208(trans-3-(o-tolyloxy)-2,3-dihydro-1H-inden-1-amine ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of serotonin uptake at human SERT in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed