BDBM50243203 (S)-1-(5-(4-(dimethylcarbamoyl)phenyl)-3-(piperidin-3-ylcarbamoyl)thiophen-2-yl)urea::CHEMBL527881

SMILES CN(C)C(=O)c1ccc(cc1)-c1cc(C(=O)N[C@H]2CCCNC2)c(NC(N)=O)s1

InChI Key InChIKey=QNLRIICTRHHTHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243203   

TargetSerine/threonine-protein kinase Chk1(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243203((S)-1-(5-(4-(dimethylcarbamoyl)phenyl)-3-(piperidi...)
Affinity DataIC50: 9nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2-associated protein 1(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243203((S)-1-(5-(4-(dimethylcarbamoyl)phenyl)-3-(piperidi...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of Cdk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed