BDBM50242956 CHEMBL4085581

SMILES Cn1cnc(COc2cc(nn2-c2ccc(cc2)C#N)C(=O)N2CCC[C@@H](N)C2)n1

InChI Key InChIKey=HGHCIXJQNBNLKL-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242956   

TargetLysine-specific histone demethylase 1A(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50242956(CHEMBL4085581)
Affinity DataIC50: 750nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50242956(CHEMBL4085581)
Affinity DataKd:  120nMAssay Description:Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed