BDBM50242674 5-((4-azido-3-iodobenzamido)methyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide::CHEMBL453042

SMILES CN(C)C(=O)n1nnc(CNC(=O)c2ccc(N=[N+]=[N-])c(I)c2)n1

InChI Key InChIKey=MFRJDQLEKDSQDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242674   

TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242674(5-((4-azido-3-iodobenzamido)methyl)-N,N-dimethyl-2...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242674(5-((4-azido-3-iodobenzamido)methyl)-N,N-dimethyl-2...)
Affinity DataIC50: 25nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed