BDBM50242658 CHEMBL4085694

SMILES NC(=O)c1cccc(NC(=O)\C=C/C(=O)N2CCCC(C2)c2ccccc2)c1

InChI Key InChIKey=DUVLGZHVLHPLOD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50242658   

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242658(CHEMBL4085694)
Affinity DataIC50: 690nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242658(CHEMBL4085694)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242658(CHEMBL4085694)
Affinity DataIC50: 692nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242658(CHEMBL4085694)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242658(CHEMBL4085694)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242658(CHEMBL4085694)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed