BDBM50242641 5-(biphenyl-3-ylcarboxamidomethyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide::CHEMBL520034

SMILES CN(C)C(=O)n1nnc(CNC(=O)c2cccc(c2)-c2ccccc2)n1

InChI Key InChIKey=DXYNBYCKZNBGQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242641   

TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242641(5-(biphenyl-3-ylcarboxamidomethyl)-N,N-dimethyl-2H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242641(5-(biphenyl-3-ylcarboxamidomethyl)-N,N-dimethyl-2H...)
Affinity DataIC50: 23nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed