BDBM50242640 CHEMBL486039::N,N-Dimethyl-5-((7-phenyloctanamido)methyl)-1Htetrazole-1-carboxamide

SMILES CN(C)C(=O)n1nnnc1CNC(=O)CCCCCCCc1ccccc1

InChI Key InChIKey=HIADSYTVDMQHFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242640   

TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242640(N,N-Dimethyl-5-((7-phenyloctanamido)methyl)-1Htetr...)
Affinity DataIC50: 570nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242640(N,N-Dimethyl-5-((7-phenyloctanamido)methyl)-1Htetr...)
Affinity DataIC50: 10nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed