BDBM50242626 CHEMBL4097232

SMILES NC(=O)c1cccc(NC(=O)\C=C/C(=O)N2CCN(CC2)c2ccc(cc2)-c2ccccc2)c1

InChI Key InChIKey=AOHKATYJFHGYRV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50242626   

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242626(CHEMBL4097232)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242626(CHEMBL4097232)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242626(CHEMBL4097232)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242626(CHEMBL4097232)
Affinity DataIC50: 9.77E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242626(CHEMBL4097232)
Affinity DataIC50: 813nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242626(CHEMBL4097232)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed