BDBM50242022 CHEMBL4104302

SMILES Nc1nccc(Oc2ccc(NC(=O)C3(CC3)C(=O)Nc3ccc(F)cc3)cc2F)c1Cl

InChI Key InChIKey=FHFKMBKXODPUFW-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50242022   

TargetEpidermal growth factor receptor(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50242022(CHEMBL4104302)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50242022(CHEMBL4104302)
Affinity DataIC50: 172nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50242022(CHEMBL4104302)
Affinity DataIC50: 279nMAssay Description:Inhibition of KIT (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50242022(CHEMBL4104302)
Affinity DataIC50: 55nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50242022(CHEMBL4104302)
Affinity DataIC50: 2.22E+3nMAssay Description:Inhibition of FLT3 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50242022(CHEMBL4104302)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 45 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50242022(CHEMBL4104302)
Affinity DataIC50: 387nMAssay Description:Inhibition of RET (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed