BDBM50241992 CHEMBL4074262

SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1

InChI Key InChIKey=VLBZFDFQVGAJSP-UHFFFAOYSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50241992   

TargetFibroblast growth factor receptor 1(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of FGFR1 (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of Axl (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of IGF1R (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of c-Src (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of c-Kit (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ALK (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 0.680nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 731nMAssay Description:Inhibition of RON (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of EPHB2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of EPHA2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ABL (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ERBB4 (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of RET (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50241992(CHEMBL4074262)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of FLT1 (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed