BDBM50241901 CHEMBL4065026

SMILES Cn1ccc2c(CCNS(=O)(=O)c3ccc(\C=C\C(=O)NO)cc3)cccc12

InChI Key InChIKey=BESZEUWJRGYGSJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50241901   

TargetHistone deacetylase 4(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241901(CHEMBL4065026)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full length HDAC4 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241901(CHEMBL4065026)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant human full length HDAC6 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241901(CHEMBL4065026)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full length HDAC8 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241901(CHEMBL4065026)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human full length HDAC1 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241901(CHEMBL4065026)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of recombinant human full length HDAC2 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed