BDBM50241660 CHEMBL4084398

SMILES CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)[C@H]1CCc2cccc(F)c12

InChI Key InChIKey=HONKOMBKMLYRBQ-UHFFFAOYSA-N

Data  1 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50241660   

TargetPolycomb protein EED(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50241660(CHEMBL4084398)
Affinity DataKd:  10nMAssay Description:Binding affinity to His tagged human EED (77 to 441 residues) expressed in Escherichia coli BL21(DE3)-T1R by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50241660(CHEMBL4084398)
Affinity DataKd:  1nMAssay Description:Binding affinity to biotin labelled human EED (78 to 441 residues) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50241660(CHEMBL4084398)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed