BDBM50241641 (+)-Homoaromoline::CHEMBL509855::Homoaromoline::Limacusine (R,S)

SMILES COc1ccc2C[C@H]3N(C)CCc4cc(OC)c(Oc5c(O)c(OC)cc6CCN(C)[C@@H](Cc7ccc(Oc1c2)cc7)c56)cc34

InChI Key InChIKey=YJRWQNIRFXVBRB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241641   

TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM50241641(CHEMBL509855 | Limacusine (R,S) | Homoaromoline | ...)
Affinity DataIC50: 5.50E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2012
Entry Details Article
PubMed
LigandPNGBDBM50241641(CHEMBL509855 | Limacusine (R,S) | Homoaromoline | ...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of dopamine transporter-mediated [3H]dopamine uptake in Wistar rat striatal synaptosomes by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed