BDBM50241489 (Z)-5-(3'-Methoxybenzylidene)-2-thioxothiazolidin-4-one::5-(3-methoxybenzylidene)-2-thioxothiazolidin-4-one::CHEMBL402427

SMILES COc1cccc(C=C2SC(S)=NC2=O)c1

InChI Key InChIKey=ZXBRDIMYFRPBGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241489   

TargetArylamine N-acetyltransferase 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50241489((Z)-5-(3'-Methoxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50241489((Z)-5-(3'-Methoxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50: 6.24E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed