BDBM50241368 CHEMBL4096875

SMILES CN(CC=Cc1ccc(cc1)C(F)(F)F)Cc1ccc2OCCc2c1

InChI Key InChIKey=CUMZMIDJUYSULN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50241368   

Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50241368(CHEMBL4096875)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50241368(CHEMBL4096875)
Affinity DataIC50: 231nMAssay Description:Inhibition of Staphylococcus aureus Newman 6His-tagged CrtN expressed in Escherichia coli BL21(DE3) assessed as reduction in staphyloxanthin levels u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50241368(CHEMBL4096875)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells after 3 mins at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50241368(CHEMBL4096875)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of CrtN in Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMed