BDBM50241183 (E)-N-(2-(1H-indol-3-yl)ethyl)-4-(3-(4-(benzyloxy)phenyl)acrylamido)piperidine-4-carboxamide::CHEMBL244160::N-(2-(1H-indol-3-yl)ethyl)-4-(3-(4-(benzyloxy)phenyl)acrylamido)piperidine-4-carboxamide

SMILES O=C(NC1(CCNCC1)C(=O)NCCc1c[nH]c2ccccc12)\C=C\c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=AOJOYIPTDUCKBP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50241183   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50241183(N-(2-(1H-indol-3-yl)ethyl)-4-(3-(4-(benzyloxy)phen...)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of recombinant GST-tagged SIRT2 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50241183(N-(2-(1H-indol-3-yl)ethyl)-4-(3-(4-(benzyloxy)phen...)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of SIRT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50241183(N-(2-(1H-indol-3-yl)ethyl)-4-(3-(4-(benzyloxy)phen...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of SIRT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed