BDBM50240897 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one::3',4',5-trihydroxy-3,7-dimethoxyflavone::CHEMBL164861::Quercetin-3,7-dimethylether

SMILES COc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(OC)c2=O

InChI Key InChIKey=LUJAXSNNYBCFEE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240897   

TargetMitogen-activated protein kinase 14(Human)
Eberhard Karls University of Tuebingen

LigandPNGBDBM50240897(3',4',5-trihydroxy-3,7-dimethoxyflavone | Querceti...)
Affinity DataIC50: 1.23E+4nMT: 2°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Eberhard Karls University of Tuebingen

LigandPNGBDBM50240897(3',4',5-trihydroxy-3,7-dimethoxyflavone | Querceti...)
Affinity DataIC50: 7.70E+3nMT: 2°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetNADPH oxidase 4(Human)
Vichem Chemie Research

Curated by ChEMBL
LigandPNGBDBM50240897(3',4',5-trihydroxy-3,7-dimethoxyflavone | Querceti...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetPlasminogen(Human)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50240897(3',4',5-trihydroxy-3,7-dimethoxyflavone | Querceti...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed