BDBM50240880 CHEMBL4060880

SMILES O=c1cc(SCc2ccccn2)nc2ccccn12

InChI Key InChIKey=BPQHMBSDSOMOQL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240880   

TargetMetabotropic glutamate receptor 5(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50240880(CHEMBL4060880)
Affinity DataIC50: 168nMAssay Description:Negative allosteric modulation of rat mGlu5 expressed in HEK293 cells assessed as inhibition of glutamate-induced intracellular calcium accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50240880(CHEMBL4060880)
Affinity DataKi:  194nMAssay Description:Displacement of [3H]MPEPy from human mGlu5 expressed in HEK293FT cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed