BDBM50240872 CHEMBL4095912

SMILES Nc1nc(Cl)c2cnn(Cc3ccc4OCOc4c3)c2n1

InChI Key InChIKey=KIJSFKWTIJSEIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240872   

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandPNGBDBM50240872(CHEMBL4095912)
Affinity DataIC50: 6.34E+3nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandPNGBDBM50240872(CHEMBL4095912)
Affinity DataIC50: 8.93E+3nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed