BDBM50240809 CHEMBL4077448

SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1cc(F)cc(F)c1O

InChI Key InChIKey=XRXNDGMCQAAXTI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240809   

TargetFibroblast growth factor receptor 1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240809(CHEMBL4077448)
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240809(CHEMBL4077448)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant human FGFR2 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240809(CHEMBL4077448)
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human FGFR3 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240809(CHEMBL4077448)
Affinity DataIC50: 280nMAssay Description:Inhibition of FGFR2 in human SNU16 cells assessed as inhibition of cell proliferation after 72 hrs by cell counting kit-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed