BDBM50240805 CHEMBL4073545

SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1ccccc1O

InChI Key InChIKey=SZRFDSHUSQGOKS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240805   

TargetFibroblast growth factor receptor 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240805(CHEMBL4073545)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human FGFR2 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240805(CHEMBL4073545)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human FGFR3 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240805(CHEMBL4073545)
Affinity DataIC50: 58nMAssay Description:Inhibition of FGFR2 in human SNU16 cells assessed as inhibition of cell proliferation after 72 hrs by cell counting kit-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240805(CHEMBL4073545)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed