BDBM50240475 CHEMBL4080361::US9969724, Example 9

SMILES Nc1noc2c(ccc(Cl)c12)N1CC[C@H](C1)NC(=O)c1ccc(cc1Cl)-n1cnnc1

InChI Key InChIKey=XLAONFHALMRZGL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240475   

TargetCoagulation factor IX(Human)
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240475(CHEMBL4080361 | US9969724, Example 9)
Affinity DataIC50: 32nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240475(CHEMBL4080361 | US9969724, Example 9)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240475(CHEMBL4080361 | US9969724, Example 9)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent