BDBM50240471 CHEMBL4069082::US9969724, Example 45

SMILES Cn1ncn(-c2ccc(C(=O)N[C@@H]3CCN(C3)c3ncc(Cl)c4c(N)noc34)c(Cl)c2)c1=O

InChI Key InChIKey=XRSYEDBIHQMIFZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240471   

TargetCoagulation factor IX(Human)
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240471(CHEMBL4069082 | US9969724, Example 45)
Affinity DataIC50: 15nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240471(CHEMBL4069082 | US9969724, Example 45)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240471(CHEMBL4069082 | US9969724, Example 45)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent