BDBM50240449 3-(3-(benzyloxy)-4-methoxyphenyl)-8H-thieno[2,3-b]pyrrolizin-8-one::3-(3-Benzyloxy-4-methoxy-phenyl)-thieno[2,3-b]pyrrolizin-8-one::CHEMBL34267::Thienopyrrolizine derivative, 4e

SMILES COc1ccc(cc1OCc1ccccc1)-c1csc2C(=O)c3cccn3-c12

InChI Key InChIKey=WHVSAKYXLTUBMB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240449   

TargetGlycogen synthase kinase-3 beta(Human)
UniversitÉ

LigandPNGBDBM50240449(CHEMBL34267 | Thienopyrrolizine derivative, 4e | 3...)
Affinity DataIC50: 5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
UniversitÉ

LigandPNGBDBM50240449(CHEMBL34267 | Thienopyrrolizine derivative, 4e | 3...)
Affinity DataIC50: 5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
UniversitÉ

LigandPNGBDBM50240449(CHEMBL34267 | Thienopyrrolizine derivative, 4e | 3...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50240449(CHEMBL34267 | Thienopyrrolizine derivative, 4e | 3...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed