BDBM50240313 CHEMBL4103516

SMILES CCCC(CCC)(c1ccc(O)c(C)c1)c1ccc(OCCN(C)C)c(C)c1

InChI Key InChIKey=PVNDGPVAGMGTLC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240313   

TargetEstrogen receptor(Human)
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50240313(CHEMBL4103516)
Affinity DataIC50: 134nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50240313(CHEMBL4103516)
Affinity DataIC50: 52nMAssay Description:Binding affinity to GST-tagged human ER alpha ligand-binding domain by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50240313(CHEMBL4103516)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as reduction in E2-induced ER-alpha-mediated transcrip...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed