BDBM50240153 (+/-)-2-((3,4-dichlorophenyl)(methyl)amino)-1-(3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone::CHEMBL254356::rac-2-((3,4-dichlorophenyl)(methyl)amino)-1-(3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone

SMILES CN(CC(=O)N1CCCC(C1CN1CCCC1)c1ccccc1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=HXWCQEQIPYCSAM-UHFFFAOYSA-N

Data  2 KI  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50240153   

TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50240153((+/-)-2-((3,4-dichlorophenyl)(methyl)amino)-1-(3-p...)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50240153((+/-)-2-((3,4-dichlorophenyl)(methyl)amino)-1-(3-p...)
Affinity DataIC50: 750nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50240153((+/-)-2-((3,4-dichlorophenyl)(methyl)amino)-1-(3-p...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50240153((+/-)-2-((3,4-dichlorophenyl)(methyl)amino)-1-(3-p...)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50240153((+/-)-2-((3,4-dichlorophenyl)(methyl)amino)-1-(3-p...)
Affinity DataIC50: 750nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50240153((+/-)-2-((3,4-dichlorophenyl)(methyl)amino)-1-(3-p...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50240153((+/-)-2-((3,4-dichlorophenyl)(methyl)amino)-1-(3-p...)
Affinity DataKi:  16nMAssay Description:Binding affinity to human urotensin-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50240153((+/-)-2-((3,4-dichlorophenyl)(methyl)amino)-1-(3-p...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed