BDBM50239958 CHEMBL4105299

SMILES N[C@@H]1CCCC[C@H]1NS(=O)(=O)c1ccc(cc1)-c1ccc(CSc2nc3CCCc3c(=O)[nH]2)cc1

InChI Key InChIKey=DPPIOMVVZPSRDW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50239958   

TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239958(CHEMBL4105299)
Affinity DataIC50: 17nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239958(CHEMBL4105299)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MMP1 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239958(CHEMBL4105299)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP8 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239958(CHEMBL4105299)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP9 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239958(CHEMBL4105299)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MMP14 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239958(CHEMBL4105299)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MMP2 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed