BDBM50239863 CHEMBL4087449

SMILES Cc1cc2CCC(Oc2cc1N1Cc2cn(Cc3ccccc3)c(=O)cc2NC1=O)c1ncccc1F

InChI Key InChIKey=SQFLORLZIWQDIK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50239863   

TargetEukaryotic initiation factor 4A-I(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239863(CHEMBL4087449)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239863(CHEMBL4087449)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239863(CHEMBL4087449)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetATP-dependent RNA helicase DHX29(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239863(CHEMBL4087449)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length recombinant human N-terminal FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed