BDBM50239789 CHEMBL4097298

SMILES COc1cncc(Cc2cc(no2)-c2ccccc2)c1

InChI Key InChIKey=RHNYFVBEYUTJIM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50239789   

TargetCytochrome P450 11B1, mitochondrial(Rat)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50239789(CHEMBL4097298)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of rat CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50239789(CHEMBL4097298)
Affinity DataIC50: 27nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50239789(CHEMBL4097298)
Affinity DataIC50: 2nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50239789(CHEMBL4097298)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human ERG after 3.5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed