BDBM50239774 CHEMBL4084775

SMILES CN1CCN(CCON=C2C(Nc3ccccc23)=C2C(=O)Nc3ccccc23)CC1

InChI Key InChIKey=HGZYVJNUFKTDLR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239774   

TargetInsulin-like growth factor 1 receptor(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239774(CHEMBL4084775)
Affinity DataIC50: 169nMAssay Description:Inhibition of IGF1R (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50239774(CHEMBL4084775)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of recombinant His-tagged human FLT3 expressed in baculovirus expression system using peptide substrate incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed