BDBM50239664 CHEMBL4088892

SMILES Cc1c2c(n[nH]1)OC(=C([C@@]2(c3cc(cc(c3)F)N4CCC(CC4)CC(=O)O)C(C)C)C#N)N

InChI Key InChIKey=LNTOYLXMWSSXMA-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50239664   

TargetGlycine hydroxymethyltransferase(malaria parasite P. falciparum)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50239664(CHEMBL4088892)
Affinity DataIC50: 110nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2019
Entry Details Article
PubMed