BDBM50239647 CHEMBL4092595

SMILES [2H]C([2H])([2H])c1[nH]nc2OC(N)=C(C#N)C(C(C)C)(c12)c1cc(cc(c1)C(F)(F)F)-c1ccc(s1)S(=O)(=O)N(C)C

InChI Key InChIKey=UWTRFJZKBCFVRC-HPRDVNIFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50239647   

TargetGlycine hydroxymethyltransferase(malaria parasite P. falciparum)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50239647(CHEMBL4092595)
Affinity DataIC50: 11nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2019
Entry Details Article
PubMed