BDBM50239644 CHEMBL4082315

SMILES CC(C)C1(c2c(C)[nH]nc2OC(N)=C1C#N)c1cc(OC(F)(F)F)cc(c1)-c1ccc(Cl)s1

InChI Key InChIKey=RZAJXRCVISAWDB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50239644   

TargetGlycine hydroxymethyltransferase(malaria parasite P. falciparum)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50239644(CHEMBL4082315)
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2019
Entry Details Article
PubMed