BDBM50239402 CHEMBL4090825

SMILES Cc1cccc2nc(Cn3cnc4c(N)ncnc34)n(-c3ccccc3)c(=O)c12

InChI Key InChIKey=KADZMZDAUYWFBW-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239402   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University of Parma

Curated by ChEMBL

LigandBDBM50239402(CHEMBL4090825)Copy SMILESCopy InChI

Affinity DataIC50: 50nMAssay Description:Inhibition of PI3Kdelta in human PBMC assessed as reduction in anti-human CD28 antibody stimulated IL-6 secretion levels after 72 hrs by ELISAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/21/2019
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University of Parma

Curated by ChEMBL

LigandBDBM50239402(CHEMBL4090825)Copy SMILESCopy InChI

Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using P...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/21/2019
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL