BDBM50239171 CHEMBL4078546

SMILES Fc1cc2[nH]cc(Cc3c[nH]c4cc(F)c(F)cc34)c2cc1F

InChI Key InChIKey=IZIJUPXVPBMXDJ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50239171   

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239171(CHEMBL4078546)
Affinity DataEC50:  187nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239171(CHEMBL4078546)
Affinity DataEC50:  1.03E+4nMAssay Description:Agonist activity at human GPR84 expressed in CHO cells assessed as beta-arrestin recruitment after 90 mins by beta-galactosidase complementation assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239171(CHEMBL4078546)
Affinity DataEC50:  52nMAssay Description:Positive allosteric modulation of recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as increase in [3H]PS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed