BDBM50238765 CHEMBL4072722

SMILES COc1ccccc1CNC[C@H]1C[C@@H]1c1cc(F)ccc1OC

InChI Key InChIKey=ZTMZRHFENROFGY-UHFFFAOYSA-N

Data  3 KI  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50238765   

Target5-hydroxytryptamine receptor 2A(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50238765(CHEMBL4072722)
Affinity DataEC50:  138nMAssay Description:Agonist activity at human 5-HT2A receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50238765(CHEMBL4072722)
Affinity DataEC50:  139nMAssay Description:Agonist activity at human 5-HT2A receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50238765(CHEMBL4072722)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human 5-HT2C-INI receptor isoform expressed in Flp-IN HEK293 cells assessed as induction of Gq-mediated calcium flux measured eve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50238765(CHEMBL4072722)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50238765(CHEMBL4072722)
Affinity DataEC50:  70nMAssay Description:Agonist activity at tTA containing TEV cleavage site-fused 5-HT2C-INI receptor isoform (unknown origin) expressed in TEV-fused beta-arrestin2 express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50238765(CHEMBL4072722)
Affinity DataEC50:  69nMAssay Description:Agonist activity at tTA containing TEV cleavage site-fused 5-HT2C-INI receptor isoform (unknown origin) expressed in TEV-fused beta-arrestin2 express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50238765(CHEMBL4072722)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-mesulergine from human 5-HT2C receptor expressed in Flp-IN HEK cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50238765(CHEMBL4072722)
Affinity DataKi:  411nMAssay Description:Displacement of [3H]-LSD from human 5-HT2B receptor expressed in HEKT cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50238765(CHEMBL4072722)
Affinity DataKi:  492nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in HEKT cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2019
Entry Details Article
PubMed