BDBM50238615 CHEMBL264967::Thiophene-2-carboxylic Acid (2S,4aR,6aR,7R,9S,10aS,10bR)-7-Carbomethoxy-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-9-yl Ester::Thiophene-3-carboxylic Acid (2S,4aR,6aR,7R,9S,10aS,10bR)-7-Carbomethoxy-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-9-yl Ester

SMILES COC(=O)[C@@H]1C[C@H](OC(=O)c2cccs2)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1ccoc1

InChI Key InChIKey=BZNOPGMFTTXDTR-UHFFFAOYSA-N

Data  6 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50238615   

TargetMu-type opioid receptor(Human)
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50238615(Thiophene-2-carboxylic Acid (2S,4aR,6aR,7R,9S,10aS...)
Affinity DataEC50:  1.15E+3nMAssay Description:Agonist activity at human recombinant mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50238615(Thiophene-2-carboxylic Acid (2S,4aR,6aR,7R,9S,10aS...)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]IOXY from human recombinant mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50238615(Thiophene-2-carboxylic Acid (2S,4aR,6aR,7R,9S,10aS...)
Affinity DataKi:  10nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50238615(Thiophene-2-carboxylic Acid (2S,4aR,6aR,7R,9S,10aS...)
Affinity DataKi:  260nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50238615(Thiophene-2-carboxylic Acid (2S,4aR,6aR,7R,9S,10aS...)
Affinity DataKi:  260nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50238615(Thiophene-2-carboxylic Acid (2S,4aR,6aR,7R,9S,10aS...)
Affinity DataKi:  1.38E+3nMAssay Description:Displacement of [125]OXY from delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Iowa

Curated by ChEMBL
LigandPNGBDBM50238615(Thiophene-2-carboxylic Acid (2S,4aR,6aR,7R,9S,10aS...)
Affinity DataKi:  1.38E+3nMAssay Description:Displacement of [125I]IOXY from human recombinant delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed