BDBM50238568 CHEMBL4100744

SMILES O=C(NCCCCc1ccccc1)n1cnc2ccccc12

InChI Key InChIKey=GVYLBEIMGTYIHI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50238568   

TargetAcid ceramidase(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238568(CHEMBL4100744)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238568(CHEMBL4100744)
Affinity DataIC50: 76nMAssay Description:Inhibition of acid ceramidase in human A375 cells using fluorogenic substrate Rbm-14-12 preincubated for 2 hrs followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238568(CHEMBL4100744)
Affinity DataIC50: 230nMAssay Description:Inhibition of acid ceramidase in human G361 cells using fluorogenic substrate Rbm-14-12 preincubated for 2 hrs followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed