BDBM50238566 CHEMBL4075846

SMILES Cc1ccc(CNC(=O)n2cnc3ccccc23)cc1

InChI Key InChIKey=SHNPPRYEYYZNRR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50238566   

TargetAcid ceramidase(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238566(CHEMBL4075846)
Affinity DataIC50: 15nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238566(CHEMBL4075846)
Affinity DataIC50: 928nMAssay Description:Inhibition of acid ceramidase in human G361 cells using fluorogenic substrate Rbm-14-12 preincubated for 2 hrs followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238566(CHEMBL4075846)
Affinity DataIC50: 505nMAssay Description:Inhibition of acid ceramidase in human A375 cells using fluorogenic substrate Rbm-14-12 preincubated for 2 hrs followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed