BDBM50238425 CHEMBL4064332

SMILES CC(C)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1

InChI Key InChIKey=AGAFBFBLFFSDKG-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50238425   

TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238425(CHEMBL4064332)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP10 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238425(CHEMBL4064332)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP1 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238425(CHEMBL4064332)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP4 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238425(CHEMBL4064332)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP11 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238425(CHEMBL4064332)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP16 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238425(CHEMBL4064332)
Affinity DataIC50: 126nMAssay Description:Binding affinity to TNKS1 in human HeLa cell extract after 2 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238425(CHEMBL4064332)
Affinity DataIC50: 200nMAssay Description:Inhibition of TNKS1 (unknown origin) expressed in HEK293 cells co-expressing TCF/LEF luciferase plasmid assessed as reduction in wnt3a ligand-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238425(CHEMBL4064332)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP2 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238425(CHEMBL4064332)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP14 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed