BDBM50238214 (2-(4-ethoxyphenyl)quinolin-4-yl)(4-(pyridin-2-yl)piperazin-1-yl)methanone::CHEMBL261118

SMILES CCOc1ccc(cc1)-c1cc(C(=O)N2CCN(CC2)c2ccccn2)c2ccccc2n1

InChI Key InChIKey=XZLOCXAETCREOE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50238214   

TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50238214((2-(4-ethoxyphenyl)quinolin-4-yl)(4-(pyridin-2-yl)...)
Affinity DataIC50: 500nMAssay Description:Inhibition of adenylate binding site of Photinus pyralis luciferase by quantitative high throughput screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Pennsylania firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50238214((2-(4-ethoxyphenyl)quinolin-4-yl)(4-(pyridin-2-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adenylate binding site of Photuris pennsylvanica luciferase by quantitative high throughput screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50238214((2-(4-ethoxyphenyl)quinolin-4-yl)(4-(pyridin-2-yl)...)
Affinity DataIC50: 600nMAssay Description:Inhibition of Photinus pyralis luciferase by Easy lite assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50238214((2-(4-ethoxyphenyl)quinolin-4-yl)(4-(pyridin-2-yl)...)
Affinity DataIC50: 400nMAssay Description:Inhibition of Photinus pyralis luciferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50238214((2-(4-ethoxyphenyl)quinolin-4-yl)(4-(pyridin-2-yl)...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Photinus pyralis luciferase by PK-Light assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed