BDBM50238207 CHEMBL4100814

SMILES Brc1ccc(cc1)-n1c(cc(\C=C2/SC(=O)NC2=O)c1-c1cccs1)-c1cccs1

InChI Key InChIKey=XQVKEBSSUVUBGA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50238207   

TargetGlutaminase liver isoform, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50238207(CHEMBL4100814)
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of recombinant human His-tagged GAB (P56 to V602 residues) expressed in Escherichia coli C41(DE3)pLysS using glutamine as substrate preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2019
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50238207(CHEMBL4100814)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of recombinant human MCF7 cells derived His-tagged GAC (L123 to S598 residues) expressed in Escherichia coli C41(DE3)pLysS using glutamine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2019
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50238207(CHEMBL4100814)
Affinity DataIC50: 754nMAssay Description:Inhibition of recombinant human His-tagged KGA (L123 to L669 residues) expressed in Escherichia coli BL21(DE3)pLysS using glutamine substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2019
Entry Details Article
PubMed