BDBM50238028 CHEMBL4070621

SMILES COC(=O)C(O)(c1cc(C)c2cccnc2c1O)C(F)(F)F

InChI Key InChIKey=UABGJLNNECVHNJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50238028   

TargetBromodomain-containing protein 4(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50238028(CHEMBL4070621)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human BRD4-BD1 (49 to 170 residues) expressed in Escherichia coli BL21(DE3) using N-C:SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHRKVGG-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50238028(CHEMBL4070621)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using biotin labelled NeC: SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHRKVGG-K as substrate preincubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed