BDBM50237856 CHEMBL254171::N-[5-(1,1-dioxo-1lambda*6*-isothiazolidin-2-yl)-1H-indazol-3-yl]-2-(4-pyridin-4-yl-phenyl)-acetamide

SMILES O=C(Cc1ccc(cc1)-c1ccncc1)Nc1n[nH]c2ccc(cc12)N1CCCS1(=O)=O

InChI Key InChIKey=KAQTYVZQFWHKBB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50237856   

TargetCyclin-dependent kinase 1(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50237856(N-[5-(1,1-dioxo-1lambda*6*-isothiazolidin-2-yl)-1H...)
Affinity DataIC50: 60nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50237856(N-[5-(1,1-dioxo-1lambda*6*-isothiazolidin-2-yl)-1H...)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50237856(N-[5-(1,1-dioxo-1lambda*6*-isothiazolidin-2-yl)-1H...)
Affinity DataIC50: 30nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed