BDBM50237735 CHEMBL4100233

SMILES CC1(C)CC2(C1)N[C@H]([C@H](c1cccc(Cl)c1F)[C@]21C(=O)Nc2cc(Cl)ccc12)C(=O)N[C@H]1CC[C@H](O)CC1

InChI Key InChIKey=HYSSPAFSTUTPOZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50237735   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandPNGBDBM50237735(CHEMBL4100233)
Affinity DataKi:  2.40nMAssay Description:Inhibition of FAM-tagged p53-based PMDM6-F peptide binding to human recombinant His-tagged MDM2 (1 to 118 residues) after 30 mins by fluorescence pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2019
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandPNGBDBM50237735(CHEMBL4100233)
Affinity DataIC50: 14nMAssay Description:Inhibition of FAM-tagged p53-based PMDM6-F peptide binding to human recombinant His-tagged MDM2 (1 to 118 residues) after 30 mins by fluorescence pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2019
Entry Details Article
PubMed