BDBM50237567 CHEMBL4092491

SMILES CC(C)[C@@H](NC(=O)OC(C)(C)C)C(=O)Nc1ccc2ncnc(Nc3cccc(c3)C(F)(F)F)c2c1

InChI Key InChIKey=JBOWGDDXNMVXGT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50237567   

TargetEpidermal growth factor receptor(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50237567(CHEMBL4092491)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of EGFR (unknown origin) measured after 40 mins by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2019
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50237567(CHEMBL4092491)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Aurora B (unknown origin) measured after 40 mins by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2019
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50237567(CHEMBL4092491)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of RAF (unknown origin) measured after 40 mins by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2019
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50237567(CHEMBL4092491)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of c-MET (unknown origin) measured after 40 mins by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50237567(CHEMBL4092491)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VEGFR2 (unknown origin) measured after 40 mins by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2019
Entry Details Article
PubMed